Intro to the Endocannabinoid System (ECS)


For those who aren’t familiar with the endocannabinoid system and its role within the human body, this post just may provide a whole new perspective and appreciation for cannabinoids as well as the hemp/cannabis plant! I want to make this as easy to digest as possible so I’ll spare you the extra wordy approach and dive right in!

Cannabis has been known to have various effects and benefits depending on how it is consumed and which cannabinoids are utilized. Hemp and it’s beautiful cannabinoids wouldn’t have the therapeutic benefits it does if our bodies didn’t already have a biological system (ECS) specifically built for interacting with its chemical compounds/cannabinoids such as CBD, CBN, CBG, THC(<0.3%) and so many others.

The endocannabinoid system…

The endocannabinoid system (ECS) was discovered in the late 80’s and early 90’s and there is still so much research to be done, for my fellow canna-nerds and biochem enthusiasts out there, that’s pretty exciting! The ECS is made up of endocannabinoids, CB1 and CB2 receptors and enzymes that are believed to impact various functions such as sleep, mood, appetite, memory, perception of pain and discomforts, and the list just goes on and on. Overall the endocannabinoid system when cared for, helps to promote internal balance and homeostasis despite external factors. There are some key factors to consider when looking at the ECS..

Cannabinoid receptors…

Cannabinoid receptors are found on the surface of cells and essentially “listen” to conditions outside the cell. They then use that information to determine the changes that need to be made inside of the cell to accommodate the appropriate cellular response in order to help maintain homeostasis and balance. 

We have two major cannabinoid receptors, CB1 & CB2. These aren’t the only receptors present within our ECS but they are the first discovered and have been most studied thus far. 

CB1 receptors tend to be the most abundant cannabinoid receptors in the brain, these receptors are what interact with THC and allow people to get that “high” feeling when using marijuana (keep in mind all of our products are hemp derived and will never contain more than .3% THC). CB2 receptors are more commonly found outside of the nervous system in places such as the immune system but both types of receptors are found throughout the entire body.

So to wrap it all up…We’re all designed with a specific internal system that is built to work with cannabinoids both from the hemp or cannabis plant as well as the endocannabinoids we produce naturally within our body. One of the main purposes of our ECS system to help maintain internal balance despite external factors. Below is a chart giving a visual of our CB1 and CB2 receptors and where they are found throughout our body! Stay tuned for more of a deep dive into the intricacies of the ECS in upcoming blogs!

Endocannabinoid System Diagram


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